Temporal Dynamic Analysis

Submitted by jdronse on Tue, 08/20/2019 - 14:37

Dear DPABI community,

I have some questions regarding temporal dynamic analysis. I have two groups of subjects, AD patients and healthy controls. I want to compare the patterns of dynamic r-fMRI indices and and their concordance.

  •  For group analysis of dynamic r-fMRI indices, do I use the CV maps? Do they have to be z-scored and smoothed?
  • Do I have to z-score the concordance maps for group analysis?
  • Is it possible to calculate the static concordance across subjects as describend in Yan et. al 2017? As I understand so far, DPABI outputs the temporal functional concordance within subjects.

Thank you and best wishes!

Julian

Forums:

YAN Chao-Gan

Wed, 08/21/2019 - 01:03

Hi Julian,

1. Some people use CV maps, but some others use STD maps. Usually they should be z-scored and smoothed.

2. Yes.

3. Yes, you can. However, you need to call the script y_KendallW_Image.m (for voxel-wise) or y_KendallW_AcrossImages.m (for volume-wise).

Best,

Chao-Gan

Yuanyuan

Tue, 07/28/2020 - 05:32

Dear Prof. Yan,

I have scanned TDA related questions posted in the forum and I'd like to add a question following your reply 1. 

You answered here with "Usually they should be z-scored and smoothed." 

But in the temporaldynamicsmetrics directory, there are only CV maps, Mean maps and Std maps (not z-scored and smoothed).  Do you mean that the results should be post-processed with z-score and smooth before group analysis? And how I can do this?

Many thanks!

Best wishes，
 
Yuanyuan Yin

YAN Chao-Gan

Thu, 07/30/2020 - 05:55

Use "Standardization" module.